Enzyme
Janus kinase
Definitions related to janus kinase:
  • (jak kinase) NonEC; family of cytoplasmic protein tyrosine kinases.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by associating with specific CYTOKINE RECEPTORS. They act upon STAT TRANSCRIPTION FACTORS in signaling pathway referred to as the JAK/STAT pathway. The name Janus kinase refers to the fact the proteins have two phosphate-transferring domains.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • (janus kinase family) A family of intracellular, non-receptor tyrosine-protein kinases. These enzymes transduce signals from certain cytokine receptors by phosphorylating and activating members of the Signal Transducer and Activator of Transcription (STAT) family of transcription factor proteins.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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