Receptor
NMDA receptor
Subclass of:
Receptors, Ionotropic Glutamate
Definitions related to n-methyl-d-aspartate receptors:
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(nmda receptor) Abbreviation for the N-methyl-D-aspartame receptor, a molecule on the surface of a brain cell that admits calcium when activated by the chemical messenger glutamate.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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(nmda receptor) Subtype of glutamate receptor to which the synthetic aminoacid NMDA is an agonist; effectors are ligand- and voltage-gated calcium channel domains or subunits; important in excitotoxicity and neural plasticity.CRISP ThesaurusNational Institutes of Health, 2006
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A protein complex that plays a role in both NMDA binding and ion transport. It is a heterotetramer consisting of 2 glutamate [NMDA] receptor subunit zeta-1 proteins and 2 epsilon subunits (glutamate [NMDA] receptor subunit epsilon-1, -2, -3 or -4).NCI ThesaurusU.S. National Cancer Institute, 2021
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(receptors, n-methyl-d-aspartate) A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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