Biologically Active Substance
P-glycoprotein
P·gly·co·pro·tein
Subclass of:
P-Glycoproteins
Definitions related to p-glycoprotein:
-
(p glycoprotein) Gene product of the multidrug resistance gene mdr-1, believed to be a membrane spanning transporter that can pump a wide variety of cytotoxic agents out of the cell.CRISP ThesaurusNational Institutes of Health, 2006
-
(atp binding cassette transporter, subfamily b, member 1) A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
Return to OpenMD Medical Dictionary
> P
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.