Disease or Syndrome
POEMS syndrome
Subclass of:
Multiple congenital anomalies;
Paraproteinemias;
Polyneuropathy
Also called:
Crow-Fukase Syndrome; PEP Syndrome; Takatsuki Disease
Definitions related to poems syndrome:
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A multisystemic disorder characterized by a sensorimotor polyneuropathy (POLYNEUROPATHIES), organomegaly, endocrinopathy, monoclonal gammopathy, and pigmentary skin changes. Other clinical features which may be present include EDEMA; CACHEXIA; microangiopathic glomerulopathy; pulmonary hypertension (HYPERTENSION, PULMONARY); cutaneous necrosis; THROMBOCYTOSIS; and POLYCYTHEMIA. This disorder is frequently associated with osteosclerotic myeloma. (From Adams et al., Principles of Neurology, 6th ed, p1335; Rev Med Interne 1997;18(7):553-62)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A syndrome characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes. It is often associated with osteosclerotic myeloma.NCI ThesaurusU.S. National Cancer Institute, 2021
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POEMS syndrome is a paraneoplastic syndrome characterized by polyradiculoneuropathy (P), organomegaly (O), endocrinopathy (E), clonal plasma cell disorder (M), and skin changes (S). Other features include papilledema, extravascular volume overload, sclerotic bone lesions, thrombocytosis/erythrocytosis, and elevated VEGF levels.OrphaNetINSERM, 2021
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POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, skin changes) is a nonautoimmune polyglandular deficiency syndrome.Merck & Co., Inc., 2020
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Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome is a rare multisystemic disease that occurs in the setting of a plasma cell dyscrasia. The pathophysiologic link between the constellation of symptoms and the underlying disease is not well understood, but the link may be related to...WebMD, 2019
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POEMS syndrome is a rare blood disorder that damages your nerves and affects other parts of your body. POEMS stands for these signs and symptoms:Mayo Foundation for Medical Education and Research
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POEMS syndrome is a rare, mulitisystem disorder. POEMS stands for the disorder's features, which may include P olyneuropathy, O rganomegaly, E ndocrinopathy, M onoclonal gammopathy, and S kin changes. Signs and symptoms may include progressive sensorimotor polyneuropathy; enlarged liver, spleen, and/or lymph nodes; a disorder of the...National Center for Advancing Translational Sciences
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