• A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2025
• Gene silencing phenomenon or technique whereby specific double stranded RNAs trigger degradation of the homologous mRNA; the specific double stranded RNAs are processed into small interfering RNAs which serve as a guide for cleavage of the homologous mRNA in the RNA induced silencing complex.
  CRISP Thesaurus
  National Institutes of Health, 2006
• Sequence-specific posttranscriptional gene silencing. It is mediated by 21- and 22-nucleotide small interfering RNAs (siRNAs) generated by ribonuclease III cleavage from longer dsRNAs.
  NCI
  U.S. National Cancer Institute, 2021
• (regulatory ncrna-mediated post-transcriptional gene silencing) The inactivation of gene expression that occurs after transcription.
  Gene Ontology Dictionary
  Gene Ontology Consortium, 2021
• (regulatory ncrna-mediated post-transcriptional gene silencing) The inactivation of gene expression that occurs after transcription.
  Gene Ontology Dictionary
  Gene Ontology Consortium, 2021
• RNA interference (RNAi), regulatory system occurring within eukaryotic cells (cells with a clearly defined nucleus) that controls the activity of genes. RNAi functions specifically to silence, or deactivate, genes. The ability of interfering RNA to silence genes was discovered in the 1990s by...
  Encyclopedia Britannica
  Encyclopedia Britannica, Inc., 2025