Disease or Syndrome
Zollinger-Ellison syndrome
[ zol-ing-er-el-uh-suhn ]
Subclass of:
Paraneoplastic Endocrine Syndromes;
Gastrointestinal Neoplasms;
Intestinal Diseases;
Stomach Diseases;
Peptic Ulcer
Definitions related to zollinger-ellison syndrome:
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A condition in which there is increased production of gastrin by a gastrin-secreting tumor (usually located in the pancreas, duodenum, or abdominal lymph nodes) that stimulates the gastric mucosa to maximal activity, with consequent gastrointestinal mucosal ulceration.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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A disorder in which tumors of the pancreatic islet cells produce large amounts of gastrin (a hormone), leading to excess acid in the stomach and, possibly, a peptic ulcer (ulcer of the stomach or the upper part of the small intestine).NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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(zollinger ellison syndrome) A syndrome characterized by the presence of a gastrin-secreting tumor, usually in the pancreas or duodenum, resulting in increased gastric acidity and formation of gastric ulcers. Signs and symptoms include abdominal pain and diarrhea. It may be sporadic or a manifestation of multiple endocrine neoplasia type 1.NCI ThesaurusU.S. National Cancer Institute, 2021
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A syndrome that is characterized by the triad of severe PEPTIC ULCER, hypersecretion of GASTRIC ACID, and GASTRIN-producing tumors of the PANCREAS or other tissue (GASTRINOMA). This syndrome may be sporadic or be associated with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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(zollinger ellison syndrome) Triad comprising intractable, sometimes fulminating atypical ulcers, extremely elevated gastic acidity, and gastrin secreting non beta islet cell tumors.CRISP ThesaurusNational Institutes of Health, 2006
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Zollinger-Ellison syndrome (ZES) is caused by a non�beta islet cell, gastrin-secreting tumor of the pancreas that stimulates the acid-secreting cells of the stomach to maximal activity, with consequent gastrointestinal mucosal ulceration. ZES may occur sporadically or as part of an autosomal dominant familial syndrome called multiple...WebMD, 2019
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Zollinger-Ellison syndrome (ZES) is a condition in which tumors called gastrinomas in the pancreas and duodenum (part of the small intestine) cause high levels of the hormone gastrin in the blood. High levels of gastrin then cause production of too much stomach acid. Signs and symptoms may include abdominal pain, peptic ulcers, vomiting...National Center for Advancing Translational Sciences
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Zollinger-Ellison syndrome (ZES) is a condition caused by a gastrin-secreting tumor that causes hypersecretion of gastric acid leading to ulcer disease. It most commonly presents with abdominal pain (70% to 100%), diarrhea (37% to 73%), and gastroesophageal reflux disease (GERD) (44%). Less common presentations include weight loss, GI...Athenahealth, Inc., 2019
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