Disease or Syndrome
acanthosis nigricans
Subclass of:
Melanosis
Definitions related to acanthosis nigricans:
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A circumscribed melanosis consisting of a brown-pigmented, velvety verrucosity or fine papillomatosis appearing in the axillae and other body folds. It occurs in association with endocrine disorders, underlying malignancy, administration of certain drugs, or as in inherited disorder.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A dermatosis characterized by thickened, hyperpigmented plaques, typically on the intertriginous surfaces and neck.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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A melanotic cutaneous lesion that develops in the axilla and other body folds. It may be idiopathic, drug-induced, or it may be associated with the presence of an endocrine disorder or malignancy.NCI ThesaurusU.S. National Cancer Institute, 2021
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Abnormal darkening of the skin in body folds and creases characterized by a velvet texture and appearance.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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Circumscribed melanosis consisting of a brown pigmented, velvety verrucosity or fine papillomatosis appearing in the axillae and other body folds; occurs in association with endocrine disorders, underlying malignancy, administration of certain drugs, or as in inherited disorder.CRISP ThesaurusNational Institutes of Health, 2006
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Although Addison may have seen a case of acanthosis nigricans (AN) before 1885 and misdiagnosed it as Addison disease, the first documented case of acanthosis nigricans was in 1889 in Germany as described by Unna and Pollitzer. By 1909, acanthosis nigricans had been described in approximately 50 patients and was suspected to be...WebMD, 2019
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Acanthosis nigricans is a skin condition characterized by areas of dark, velvety discoloration in body folds and creases. The affected skin can become thickened. Most often, acanthosis nigricans affects your armpits, groin and neck.Mayo Foundation for Medical Education and Research
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Acanthosis nigricans (AN) is a skin disorder in which there is darker, thick, velvety skin in body folds and creases. This condition usually appears slowly and doesn't cause any symptoms other than skin changes. Eventually, dark, velvety skin with very visible markings and creases appears in the armpits, groin and neck folds, and over...National Center for Advancing Translational Sciences
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Acanthosis nigricans (AN) is a cutaneous disorder manifested by symmetric, hypertrophic, papillomatous, velvety, hyperpigmented plaques commonly found on flexural and intertriginous areas. It is associated with a wide array of medical conditions. AN may present at birth or in early childhood with a familial association, but is most...Athenahealth, Inc., 2019
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