Cell Component
adherens junction
Subclass of:
Intercellular Junctions
Definitions related to adherens junction:
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A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.Gene Ontology DictionaryGene Ontology Consortium, 2021
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(anchoring junction) Anchoring junctions typically are observed as "spot welds" between cells in many types of epithelia. Detail structures can be seen only with EM.NCI ThesaurusU.S. National Cancer Institute, 2021
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Anchoring points where the CYTOSKELETON of neighboring cells are connected to each other. They are composed of specialized areas of the plasma membrane where bundles of the ACTIN CYTOSKELETON attach to the membrane through the transmembrane linkers, CADHERINS, which in turn attach through their extracellular domains to cadherins in the neighboring cell membranes. In sheets of cells, they form into adhesion belts (zonula adherens) that go all the way around a cell.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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