Neoplastic Process
adrenocortical carcinoma
[ uh-dree-noh-kawr-ti-kuhl kahr-suh-noh-muh ]
Subclass of:
Tumors of Adrenal Cortex;
Adenocarcinoma
Definitions related to adrenocortical carcinoma:
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(carcinoma, adrenocortical, malignant) A malignant epithelial neoplasm arising from adrenal cortical cells.CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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A malignant neoplasm of the adrenal cortex that may produce hormones such as cortisol, aldosterone, estrogen, or testosterone.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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A malignant neoplasm of the ADRENAL CORTEX. Adrenocortical carcinomas are unencapsulated anaplastic (ANAPLASIA) masses sometimes exceeding 20 cm or 200 g. They are more likely to be functional than nonfunctional, and produce ADRENAL CORTEX HORMONES that may result in hypercortisolism (CUSHING SYNDROME); HYPERALDOSTERONISM; and/or VIRILISM.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A rare cancer that forms in the outer layer of tissue of the adrenal gland (a small organ on top of each kidney that makes steroid hormones, adrenaline, and noradrenaline to control heart rate, blood pressure, and other body functions).NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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(adrenal cortex carcinoma) A rare, usually large (greater than 5cm), malignant epithelial tumor arising from the adrenal cortical cells. Symptoms are usually related to the excessive production of hormones, and include Cushing's syndrome and virilism in women. Common sites of metastasis include liver, lung, bone, and retroperitoneal lymph nodes. Advanced radiologic procedures have enabled the detection of small tumors, resulting in the improvement of the 5-year survival.NCI ThesaurusU.S. National Cancer Institute, 2021
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Adrenocortical carcinomas (ACs) are uncommon malignancies that can have protean clinical manifestations. A majority of cases are metastatic at the time of diagnosis, with the most common sites of spread being the local periadrenal tissue, lymph nodes, lungs, liver, and bone.WebMD, 2019
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Adrenocortical carcinoma is a rare cancer affecting the outside of the adrenal glands (adrenal cortex). These glands are on top of each kidney and are responsible for producing certain hormones and keeping blood pressure at normal levels. Adrenocortical carcinoma is relatively frequent in children compared to many other cancers, although...National Center for Advancing Translational Sciences
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