Disease or Syndrome
Adrenogenital syndrome
Subclass of:
Disorders of Sex Development
Also called:
Adrenal Virilism
Definitions related to adrenogenital syndrome:
  • Abnormal SEX DIFFERENTIATION or congenital DISORDERS OF SEX DEVELOPMENT caused by abnormal levels of steroid hormones expressed by the GONADS or the ADRENAL GLANDS, such as in CONGENITAL ADRENAL HYPERPLASIA and ADRENAL CORTEX NEOPLASMS. Due to abnormal steroid biosynthesis, clinical features include VIRILISM in females; FEMINIZATION in males; or precocious sexual development in children.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Adrenogenital syndrome is also known as congenital adrenal hyperplasia, which results from disorders of steroid hormone production in the adrenal glands leading to a deficiency of cortisol. The pituitary gland reacts by increased secretion of corticotropin, which in turn causes the adrenal glands to overproduce certain intermediary hormones which have testosterone-like effects.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • Adrenal virilism is a syndrome in which excessive adrenal androgens cause virilization. Diagnosis is clinical and confirmed by elevated androgen levels with and without dexamethasone suppression; determining the cause may involve adrenal imaging. Treatment depends on the cause.
    Merck Manuals
    Merck & Co., Inc., 2025
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