Vitamin
alpha-tocopherol
al·pha·to·coph·er·ol [ al-fuh-toh-kof-uh-rawl, -rol ]
Brand Names:
Carni Q-Gel Forte; Infuvite; Infuvite Pediatric; MVI Pediatric; Natelle; Vital E- 500; Vital E- A + D3; Vital E- Newborn; Vital E- Repro
More Information:
Definitions related to alpha tocopherol:
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(alpha-tocopherol) A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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(alpha-tocopherol) The orally bioavailable alpha form of the naturally-occurring fat-soluble vitamin E, with potent antioxidant and cytoprotective activities. Upon administration, alpha-tocopherol neutralizes free radicals, thereby protecting tissues and organs from oxidative damage. Alpha-tocopherol gets incorporated into biological membranes, prevents protein oxidation and inhibits lipid peroxidation, thereby maintaining cell membrane integrity and protecting the cell against damage. In addition, alpha-tocopherol inhibits the activity of protein kinase C (PKC) and PKC-mediated pathways. Alpha-tocopherol also modulates the expression of various genes, plays a key role in neurological function, inhibits platelet aggregation and enhances vasodilation. Compared with other forms of tocopherol, alpha-tocopherol is the most biologically active form and is the form that is preferentially absorbed and retained in the body.NCI ThesaurusU.S. National Cancer Institute, 2021
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(alpha-tocopherol) Tocopherol with three methyl groups on its chromanol ring.CRCH Nutrition TerminologyCancer Research Center of Hawaii, University of Hawaii, 2021
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(d-alpha-tocopherol) A naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties. Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acids), d-alpha-Tocopherol is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, resulting in a decrease in prostaglandin production. Vitamin E also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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