Organic Chemical
aminopterin Audio
[ a-mih-nop-teh-rin ]
Definitions related to aminopterin:
  • A folic acid derivative used as a rodenticide that has been shown to be teratogenic.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A synthetic derivative of pterins with antineoplastic and immunosuppressive properties. As a folate analogue, aminopterin competes for the folate binding site of the enzyme dihydrofolate reductase, thereby blocking tetrahydrofolate synthesis, and resulting in depletion of nucleotide precursors and inhibition of DNA, RNA and protein synthesis. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • An anticancer drug that belongs to the family of drugs called antimetabolites.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • Folic acid derivative used as a rodenticide that has been shown to be teratogenic.
    CRISP Thesaurus
    National Institutes of Health, 2006
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