Organic Chemical
aminopterin
[ a-mih-nop-teh-rin ]
Definitions related to aminopterin:
-
A folic acid derivative used as a rodenticide that has been shown to be teratogenic.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
-
A synthetic derivative of pterins with antineoplastic and immunosuppressive properties. As a folate analogue, aminopterin competes for the folate binding site of the enzyme dihydrofolate reductase, thereby blocking tetrahydrofolate synthesis, and resulting in depletion of nucleotide precursors and inhibition of DNA, RNA and protein synthesis. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
-
An anticancer drug that belongs to the family of drugs called antimetabolites.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
-
Folic acid derivative used as a rodenticide that has been shown to be teratogenic.CRISP ThesaurusNational Institutes of Health, 2006
Return to OpenMD Medical Dictionary
> A
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.