Biologically Active Substance
amyloid protein
am·y·loid pro·tein [ am-uh-loid proh-teen, -tee-in ]
Subclass of:
Amyloid
Definitions related to amyloid proteins:
  • (amyloid) An insoluble, fibrous aggregate of misfolded proteins or protein fragments. These fibrillar structures usually exhibit a cross-beta-sheet conformation. Deposition of amyloid aggregates is associated with a number of pathologies including amyloidosis and several neurodegenerative disorders.
    NCI
    U.S. National Cancer Institute, 2021
  • Extracellular glycoprotein that accumulates in certain pathological conditions, e.g., the paired helical filaments of neuritic plaques in Alzheimer's disease and Down's syndrome; use this term for both the precursor and beta form.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • (amyloidogenic proteins) Proteins that form the core of amyloid fibrils. For example, the core of amyloid A is formed from amyloid A protein, also known as serum amyloid A protein or SAA protein.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.