Pharmacologic Substance
anthralin
Brand Names:
Drithocreme; Dritho-Scalp; Micanol; Zithranol; Zithranol-RR
Effect:
Decreased DNA Replication; Decreased Mitosis; Decreased Protein Synthesis
May Treat:
Psoriasis
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to anthralin:
  • A natural anthraquinone derivative, anti-psoriatic and anti-inflammatory Anthralin (dithranol) controls skin growth by reducing DNA synthesis and mitotic activity in the hyperplastic epidermis, restoring a normal rate of cell proliferation and keratinization. Used topically in the treatment of psoriasis, dermatoses, and alopecia areata, it is also used in biomedical research due to its effect on EGFR autophosphorylation. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • An anthracene derivative that disrupts function and structure of MITOCHONDRIA and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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