• A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2025
• Constriction in the opening of the aortic valve or of the supravalvular or subvalvular regions.
  CRISP Thesaurus
  National Institutes of Health, 2006
• Narrowing of the orifice of the aortic valve.
  NCI
  U.S. National Cancer Institute, 2021
• Obstruction of flow across a aortic heart valve due to immobility reduced elasticity of the leaflets and/or a restricted orifice.
  U.S. FDA Glossary
  U.S. Food & Drug Administration, 2021
• The presence of a stenosis (narrowing) of the aortic valve.
  Human Phenotype Ontology (HPO)
  The Human Phenotype Ontology Project, 2025
• Aortic stenosis (AS) is narrowing of the aortic valve, obstructing blood flow from the left ventricle to the ascending aorta during systole. Causes include a congenital bicuspid valve, idiopathic degenerative sclerosis with calcification, and rheumatic fever. Untreated AS progresses to become symptomatic with one or more of the classic...
  Merck Manuals
  Merck & Co., Inc., 2025
• Aortic stenosis is the obstruction of blood flow across the aortic valve (see the image below). Among symptomatic patients with medically treated moderate-to-severe aortic stenosis, mortality from the onset of symptoms is approximately 25% at 1 year and 50% at 2 years.
  Medscape
  WebMD, 2025
• Aortic valve stenosis - or aortic stenosis - occurs when the heart's aortic valve narrows. This narrowing prevents the valve from opening fully, which reduces or blocks blood flow from your heart into the main artery to your body (aorta) and onward to the rest of your body.
  Mayo Clinic
  Mayo Foundation for Medical Education and Research, 2025
• Aortic valve stenosis (AVS) is a condition characterized by narrowing of the heart's aortic valve opening. This narrowing prevents the valve from opening fully, which obstructs blood flow from the heart into the aorta, and onward to the rest of the body. AVS can range from mild to severe. Signs and symptoms typically develop when the...
  NIH Genetic and Rare Diseases
  National Center for Advancing Translational Sciences
• Aortic stenosis (AS) represents obstruction of blood flow across the aortic valve due to pathologic narrowing. It is a progressive disease that presents after a long subclinical period with symptoms of decreased exvercise capacity, exertional chest pain (angina), syncope, and heart failure.
  Epocrates
  Athenahealth, Inc., 2019
• Aortic stenosis, narrowing of the passage between the left lower chamber (ventricle) of the heart and the aorta, the principal artery of the systemic circulation. The defect is most often in the valve at the mouth of the aorta but may be just above or below the valve (supravalvular and subvalvular...
  Encyclopedia Britannica
  Encyclopedia Britannica, Inc., 2025