Pharmacologic Substance
atovaquone
Brand Names:
Malarone; Mepron
Effect:
Decreased Metabolic Rate
May Prevent:
Pneumonia, Pneumocystis; Toxoplasmosis, Cerebral
May Treat:
Pneumonia, Pneumocystis;
Toxoplasmosis, Cerebral
More Information:
Definitions related to atovaquone:
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A hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A synthetic hydroxynaphthoquinone with antiprotozoal activity. Atovoquone blocks the mitochondrial electron transport at complex III of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death.NCI ThesaurusU.S. National Cancer Institute, 2021
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Broad-spectrum antiparasitic drug found to be active against Pneumocystis carinii pneumonia in AIDS patients.CRISP ThesaurusNational Institutes of Health, 2006
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