Pharmacologic Substance
azaserine
Subclass of:
Serine
Definitions related to azaserine:
  • A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Antibiotic substance produced by various Streptomyces species. It is an inhibitor of enzymatic activities that involve glutamine and is used as an antineoplastic and immunosuppressive agent.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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