Pharmacologic Substance
batimastat
[ ba-tih-muh-stat ]
Definitions related to batimastat:
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A synthetic hydroxamate with potential antineoplastic activity. Batimastat binds covalently to the zinc ion in the active site of matrix metalloproteinases (MMPs), thereby inhibiting the action of MMPs, inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. Batimastat is a matrix metalloproteinase inhibitor.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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