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Related terms:
intrahepatic cholestasis
liver cirrhosis
Alagille syndrome
Disease or Syndrome
biliary cirrhosis Audio
[ bil-ee-er-ee-bil-yuh-ree cir-rho-sis ]
Subclass of:
Intrahepatic Cholestasis; Liver Cirrhosis
Definitions related to biliary cirrhosis:
  • Cirrhosis of the liver caused either by destruction of the intrahepatic bile ducts (primary biliary cholangitis) or blockage of the extrahepatic bile ducts (secondary biliary cholangitis).
    U.S. FDA Glossary
    U.S. Food & Drug Administration, 2021
  • Progressive destruction of the small-to-medium bile ducts of the intrahepatic biliary tree, which leads to progressive cholestasis and often end-stage liver disease.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • (liver cirrhosis, biliary) FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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