Pathologic Function
bone necrosis
bone ne·cro·sis [ bohn nuh-kroh-sis, ne- ]
Subclass of:
Bone Diseases;
Necrosis
Also called:
Aseptic necrosis; Avascular necrosis; Ischemic necrosis; Ischemic Necrosis of Bone
Definitions related to bone necrosis:
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Death of a bone or part of a bone, either atraumatic or posttraumatic.CRISP ThesaurusNational Institutes of Health, 2006
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Death of bone tissue due to traumatic or nontraumatic causes.NCI ThesaurusU.S. National Cancer Institute, 2021
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(osteonecrosis) Osteonecrosis is a disease caused by reduced blood flow to bones in the joints. In people with healthy bones, new bone is always replacing old bone. In osteonecrosis, the lack of blood causes the bone to break down faster than the body can make enough new bone. The bone starts to die and may break down. You can have osteonecrosis in one or several bones. It is most common in the upper leg. Other common sites are your upper arm and your knees, shoulders and ankles. The disease can affect men and women of any age, but it usually strikes in your thirties, forties or fifties. At first, you might not have any symptoms. As the disease gets worse, you will probably have joint pain that becomes more severe. You may not be able to bend or move the affected joint very well. No one is sure what causes the disease. Risk factors include Long-term steroid treatment; Alcohol misuse; Joint injuries; Having certain diseases, including arthritis and cancer . Doctors use imaging tests and other tests to diagnose osteonecrosis. Treatments include medicines, using crutches, limiting activities that put weight on the affected joints, electrical stimulation and surgery. NIH: National Institute of Arthritis and Musculoskeletal and Skin DiseasesMedlinePlusU.S. National Library of Medicine, 2021
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(osteonecrosis) A disorder characterized by necrotic changes in the bone tissue due to interruption of blood supply. Most often affecting the epiphysis of the long bones, the necrotic changes result in the collapse and the destruction of the bone structure.Common Terminology Criteria for Adverse EventsU.S. National Institutes of Health, 2021
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Osteonecrosis is a focal infarct of bone that may be caused by specific etiologic factors or may be idiopathic. It can cause pain, limitation of motion, joint collapse, and secondary osteoarthritis. Diagnosis is by x-rays and MRI. In early stages, surgical procedures may slow or prevent progression. In later stages, joint replacement may...Merck & Co., Inc., 2020
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Osteonecrosis, death of bone tissue that may result from infection, as in osteomyelitis, or deprivation of blood supply, as in fracture, dislocation, Caisson disease (decompression sickness), or radiation sickness. In all cases, blood circulation in the affected area ceases, bone cells die, and the...Encyclopedia Britannica, Inc., 2020
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