Functional Concept
buccalmucosa
Definitions related to buccal route of drug administration:
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(buccal) Administration directed toward the cheek, generally from within the mouth. (FDA)CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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(buccal route of administration) Administration of a substance through the mucosal membrane on the inside of the cheek or the back of the mouth. Buccal route bypasses first pass metabolism and avoids pre-systemic elimination in the gastrointestinal tract. The buccal environment is well supplied with both vascular and lymphatic drainage and is well suited for a retentive device. This is a feasible alternative for systemic delivery of orally inefficient drugs, such as peptide and protein drug molecules.NCI ThesaurusU.S. National Cancer Institute, 2021
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