Pharmacologic Substance
bupivacaine hydrochloride Audio
[ byoo-pih-vuh-kane hy-droh-klor-ide ]
Effect:
Decreased Organized Electrical Activity; Local Anesthesia
May Prevent:
Pain
May Treat:
Pain, Postoperative
More Information:
ChemID; DailyMed; PDR
Definitions related to bupivacaine hydrochloride:
  • A drug used to relieve pain by blocking signals at nerve endings. It is being studied in the relief of pain following surgery for cancer. It is a type of local anesthetic.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A long-acting, amide-type local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation.
    NCI
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.