Biologically Active Substance
C-peptide
c·pep·tide [ see pep-tide ]
Subclass of:
Proinsulin
Definitions related to c-peptide:
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The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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C-peptide is a peptide composed of 31 amino acids. It is released from the pancreatic beta-cells during cleavage of insulin from proinsulin.WebMD, 2019
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