Biologically Active Substance
calreticulin
Subclass of:
Intracellular Calcium-Sensing Proteins; Lectin
Definitions related to calreticulin:
  • A multifunctional protein that is found primarily within membrane-bound organelles. In the ENDOPLASMIC RETICULUM it binds to specific N-linked oligosaccharides found on newly-synthesized proteins and functions as a MOLECULAR CHAPERONE that may play a role in PROTEIN FOLDING or retention and degradation of misfolded proteins. In addition calreticulin is a major storage form for CALCIUM and functions as a calcium-signaling molecule that can regulate intracellular calcium HOMEOSTASIS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Highly conserved calcium binding protein within non-muscle cell endoplasmic reticulum and smooth muscle sarcoplasmic reticulum.
    CRISP Thesaurus
    National Institutes of Health, 2006
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