Biologically Active Substance
calreticulin
Subclass of:
Intracellular Calcium-Sensing Proteins;
Lectin
Definitions related to calreticulin:
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A multifunctional protein that is found primarily within membrane-bound organelles. In the ENDOPLASMIC RETICULUM it binds to specific N-linked oligosaccharides found on newly-synthesized proteins and functions as a MOLECULAR CHAPERONE that may play a role in PROTEIN FOLDING or retention and degradation of misfolded proteins. In addition calreticulin is a major storage form for CALCIUM and functions as a calcium-signaling molecule that can regulate intracellular calcium HOMEOSTASIS.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Highly conserved calcium binding protein within non-muscle cell endoplasmic reticulum and smooth muscle sarcoplasmic reticulum.CRISP ThesaurusNational Institutes of Health, 2006
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