Pharmacologic Substance
cannabinol Audio
can·nab·i·nol [ kuh-nab-uh-nawl, -nol, kan-uh-buh- ]
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to cannabinol:
  • A cannabinoid isolated from the plant Cannabis that is a metabolite of tetrahydrocannabinol (THC), with potential immunosuppressive and anti-inflammatory activities. Cannabinol preferentially binds to the cannabinoid G-protein coupled receptor CB2, which is mainly expressed on a variety of immune cells, such as T-cells, B-cells, macrophages and dendritic cells. Stimulation of CB2 receptors by cannabinol may both trigger apoptosis in these cells and inhibit the production of a variety of cytokines. Cannabinol exerts minimal affinity for CB1 and has a weak effect on the central nervous system.
    NCI
    U.S. National Cancer Institute, 2021
  • A physiologically inactive constituent of Cannabis sativa L.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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