Antibiotic
carbenicillin
[ kahr-ben-uh-sil-in ]
Effect:
Decreased Cell Wall Synthesis & Repair
May Treat:
Gram-Negative Bacterial Infections;
Prostatitis;
Urinary Tract Infections
Definitions related to carbenicillin:
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A broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis.NCI ThesaurusU.S. National Cancer Institute, 2021
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Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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