Pharmacologic Substance
caspofungin
Brand Names:
Cancidas
Effect:
Decreased Cell Wall Integrity
May Treat:
Aspergillosis; Candidemia
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to caspofungin:
  • A cyclic lipopeptide echinocandin and beta-(1,3)-D-glucan synthase inhibitor that is used to treat internal or systemic MYCOSES.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • An antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. Caspofungin inhibits 1,3-beta-glucan synthase, resulting in decreased synthesis of beta(1,3)-D-glucan (an essential component of the fungal cell wall), weakening of the fungal cell wall, and fungal cell wall rupture. This agent is active against Aspergillus and Candida species.
    NCI
    U.S. National Cancer Institute, 2021
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