Pharmacologic Substance
caspofungin
Brand Names:
Cancidas
Effect:
Decreased Cell Wall Integrity
May Treat:
Aspergillosis; Candidemia
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to caspofungin:
  • A cyclic lipopeptide echinocandin and beta-(1,3)-D-glucan synthase inhibitor that is used to treat internal or systemic MYCOSES.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • An antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. Caspofungin inhibits 1,3-beta-glucan synthase, resulting in decreased synthesis of beta(1,3)-D-glucan (an essential component of the fungal cell wall), weakening of the fungal cell wall, and fungal cell wall rupture. This agent is active against Aspergillus and Candida species.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.