Antibiotic
cefaclor
[ sef-uh-klawr, -klohr ]
Effect:
Decreased Cell Wall Synthesis & Repair
May Treat:
Bone Diseases, Infectious;
Bronchitis;
Escherichia coli Infections;
Haemophilus Infections;
Klebsiella Infections;
Otitis Media;
Pharyngitis;
Pneumonia, Bacterial;
Proteus Infections;
Skin Diseases, Bacterial;
Soft Tissue Infections;
Staphylococcal Infections;
Streptococcal Infections;
Urinary Tract Infections
More Information:
Definitions related to cefaclor:
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A beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefaclor binds to and inactivates penicillin-binding proteins (PBP) located in bacterial cytoplasmic membranes. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI ThesaurusU.S. National Cancer Institute, 2021
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Semisynthetic, broad-spectrum antibiotic derivative of CEPHALEXIN.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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