Antibiotic
cefotaxime
Brand Names:
Claforan
Effect:
Decreased Cell Wall Synthesis & Repair
May Treat:
Acinetobacter Infections; Bacteroides Infections; Bone Diseases, Infectious; Clostridium Infections; Escherichia coli Infections; Fusobacterium Infections; Gonorrhea; Haemophilus Infections; Klebsiella Infections; Meningitis, Bacterial; Pelvic Inflammatory Disease; Peritonitis; Pneumonia, Bacterial; Proteus Infections; Pseudomonas Infections; Salmonella Infections; Sepsis; Serratia Infections; Skin Diseases, Bacterial; Soft Tissue Infections; Staphylococcal Infections; Streptococcal Infections; Urinary Tract Infections
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to cefotaxime:
  • A third generation semisynthetic cephalosporin antibiotic with bactericidal activity. Cefotaxime inhibits mucopeptide synthesis by binding to and inactivating penicillin binding proteins thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Semisynthetic broad-spectrum cephalosporin.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.