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Chemical
challenge agent
chal·lenge a·gent
Definitions related to challenge agent:
  • A non-investigational medicinal product (NIMP) given to trial subjects to produce a physiological response that is necessary before the pharmacological action of the investigational medicinal product can be assessed.
    CDISC Terminology
    Clinical Data Interchange Standards Consortium (CDISC), 2021
  • A type of substance that is given to healthy subjects in order to induce a physiological response that the investigational medicinal product is intended to counter or treat.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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