• Any condition in which the release of bile from the liver is blocked. The blockage can occur in the liver (intrahepatic cholestasis) or in the bile ducts (extrahepatic cholestasis).
  NCI Dictionary of Cancer Terms
  U.S. National Cancer Institute, 2021
• Diminished or obstructed bile flow.
  NICHD Pediatric Terminology
  U.S. National Cancer Institute, 2021
• Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2021
• Impairment of the bile flow caused by obstruction within the liver, or outside the liver in the bile duct system.
  NCI Thesaurus
  U.S. National Cancer Institute, 2021
• Stoppage or suppression of bile by intrahepatic or extrahepatic causes.
  CRISP Thesaurus
  National Institutes of Health, 2006
• Cholestasis is reduction or stoppage of bile flow. Bile is the digestive fluid produced by the liver. Disorders of the liver, bile duct, or pancreas can cause cholestasis.
  Merck Manuals
  Merck & Co., Inc., 2020
• Cholestasis is defined as a decrease in bile flow due to impaired secretion by hepatocytes or to obstruction of bile flow through intra-or extrahepatic bile ducts. Therefore, the clinical definition of cholestasis is any condition in which substances normally excreted into bile are retained.
  Medscape
  WebMD, 2019