Neoplastic Process
chordoma
[ kor-doh-muh ]
Subclass of:
Neoplasms, Germ Cell and Embryonal
Etymology:
Greek chorde = cord + -oma = tumor or new growth
Limited in usage to a neoplasm of the spinal cord.
Limited in usage to a neoplasm of the spinal cord.
Definitions related to chordoma:
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(chordoma, malignant) A malignant bone neoplasm arising from the remnants of the fetal notochord.CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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A chordoma is a tumors that arises from embryonic remnants of the notochord along the length of the neuraxis. Chordomas generally occur in the sacrum, intracranially at the clivus, or along the spinal axis.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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A malignant bone tumor arising from the remnants of the fetal notochord. Although it can occur at all ages, it is more frequently seen in middle-aged adults. The most frequent sites of involvement are the sacrococcygeal area, spheno-occipital area, and cervico-thoraco-lumbar spine. Microscopically, chordomas are composed of cells that form cords and lobules, separated by mucoid intercellular tissue. Some of the cells are large (physaliphorous) and have vacuolated cytoplasm and prominent vesicular nuclei. Other tumor cells are small with small nuclei without visible nucleoli. Chordomas tend to recur and may metastasize. The most common sites of metastasis are the skin and bone.NCI ThesaurusU.S. National Cancer Institute, 2021
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A malignant tumor arising from the embryonic remains of the notochord. It is also called chordocarcinoma, chordoepithelioma, and notochordoma. (Dorland, 27th ed)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A type of bone cancer that usually starts in the lower spinal column or at the base of the skull.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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Malignant tumor arising from the embryonic remains of the notochord; also called chordocarcinoma, chordoepithelioma, and notochordoma.CRISP ThesaurusNational Institutes of Health, 2006
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Chordomas are rare tumors that arise from embryonic notochordal remnants along the length of the neuraxis at developmentally active sites. These sites are the ends of the neuraxis and the vertebral bodies.WebMD, 2019
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A chordoma is a rare tumor that develops from cells of the notochord, a structure that is present in the developing embryo and is important for the development of the spine. The notochord usually disappears before birth, though a few cells may remain embedded in the bones of the spine or at the base of the skull. Chordomas typically...National Center for Advancing Translational Sciences
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