Pharmacologic Substance
cilengitide
[ sy-len-gih-tide ]
Definitions related to cilengitide:
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A cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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A substance that is being studied as an anticancer and antiangiogenesis drug.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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