Pharmacologic Substance
cilengitide Audio
[ sy-len-gih-tide ]
Definitions related to cilengitide:
  • A cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A substance that is being studied as an anticancer and antiangiogenesis drug.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.