Pharmacologic Substance
cisapride
Effect:
Increased Enteric Nervous System Acetylcholine Activity; Increased Esophageal Motility; Increased LES Tone
May Treat:
Constipation; Dyspepsia; Gastroesophageal Reflux; Gastroparesis
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to cisapride:
  • A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A substituted piperidinyl benzamide prokinetic agent. Cisapride facilitates release of acetylcholine from the myenteric plexus, resulting in increased gastrointestinal motility. In addition, cisapride has been found to act as a serotonin agonist, stimulating type 4 receptors, and a serotonin 5-HT3 receptor antagonist.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Cis-4-amino-5-chloro-N-(1-(3- (p-fluorophenoxy)propyl)-3-methoxy-4- piperidyl)-o-anisamide; peristaltic stimulant under clinical evaluation for constipation, gastroparesis, intestinal pseudoobstruction, and other GI motility disorders.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.