Neoplastic Process
clonal evolution
clon·al ev·o·lu·tion
Subclass of:
Cell physiology
Definitions related to clonal evolution:
  • The process by which a normal cell accumulates genetic changes that allow it to become a tumor-causing cell and furthers its development to more malignant states.
    NCI
    U.S. National Cancer Institute, 2021
  • The process of accumulation of genetic and epigenetic changes over time in individual cells and the effect of the changes on CELL PROLIFERATION.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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