Pharmacologic Substance
clopidogrel
Brand Names:
Plavix
Effect:
Decreased Platelet Aggregation
May Prevent:
Cerebral Infarction; Coronary Thrombosis; Myocardial Infarction
More Information:
Definitions related to clopidogrel:
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A thienopyridine, with antiplatelet activity. Clopidogrel targets, irreversibly binds to and alters the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor, inhibiting ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, and inhibiting fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time.NCI ThesaurusU.S. National Cancer Institute, 2021
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A ticlopidine analog and platelet purinergic P2Y receptor antagonist that inhibits adenosine diphosphate-mediated PLATELET AGGREGATION. It is used to prevent THROMBOEMBOLISM in patients with ARTERIAL OCCLUSIVE DISEASES; MYOCARDIAL INFARCTION; STROKE; or ATRIAL FIBRILLATION.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Inhibits platelet aggregationCRISP ThesaurusNational Institutes of Health, 2006
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