Pharmacologic Substance
clopidogrel
Brand Names:
Plavix
Effect:
Decreased Platelet Aggregation
May Prevent:
Cerebral Infarction; Coronary Thrombosis; Myocardial Infarction
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to clopidogrel:
  • A thienopyridine, with antiplatelet activity. Clopidogrel targets, irreversibly binds to and alters the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor, inhibiting ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, and inhibiting fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A ticlopidine analog and platelet purinergic P2Y receptor antagonist that inhibits adenosine diphosphate-mediated PLATELET AGGREGATION. It is used to prevent THROMBOEMBOLISM in patients with ARTERIAL OCCLUSIVE DISEASES; MYOCARDIAL INFARCTION; STROKE; or ATRIAL FIBRILLATION.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • Inhibits platelet aggregation
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.