Cell Component
coiled body
Subclass of:
Nuclear Bodies
Definitions related to coiled bodies:
  • (cajal body) A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
    Gene Ontology Dictionary
    Gene Ontology Consortium, 2021
  • A distinct subnuclear domain enriched in splicesomal snRNPs (RIBONUCLEOPROTEINS, SMALL NUCLEAR) and p80-coilin.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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