Hormone
cortisone acetate
cor·ti·sone ac·e·tate
Effect:
Carbohydrate Metabolism Alteration; Decreased Cellular Migration; Decreased Glucocorticoid Secretion; Decreased Leukotriene Activity; Decreased Lysosomal Function; Decreased Prostaglandin Activity; Decreased Protein Synthesis; Decreased Thromboxane Activity; Lipid Metabolism Alteration
May Prevent:
Arthritis, Gouty; Arthritis, Rheumatoid
May Treat:
Adrenal Insufficiency;
Asthma;
Berylliosis;
Bursitis;
Choroiditis;
Colitis, Ulcerative;
Collagen Diseases;
Dermatitis Herpetiformis;
Dermatitis, Atopic;
Dermatitis, Exfoliative;
Dermatitis, Seborrheic;
Dermatomyositis;
Erythema Multiforme;
Hypercalcemia;
Iritis;
Keratitis;
Leukemia;
Lupus Erythematosus, Systemic;
Mycosis Fungoides;
Nephrotic Syndrome;
Pemphigus;
Psoriasis;
Purpura, Thrombocytopenic, Idiopathic;
Rheumatic Diseases;
Rhinitis, Allergic;
Sarcoidosis;
Spondylitis, Ankylosing;
Thyroiditis;
Tuberculosis, Pulmonary
More Information:
Definitions related to cortisone acetate:
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The acetate ester of cortisone that is used mainly for replacement therapy in adrenocortical insufficiency and in the treatment of many allergic and inflammatory disorders.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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The acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA transcription. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators.NCI ThesaurusU.S. National Cancer Institute, 2021
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