Enzyme
creatine kinase
cre·a·tine ki·nase
Definitions related to creatine kinase:
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A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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An enzyme complex that can reversibly convert ATP and creatine to phosphocreatine and ADP. Cytosolic creatine kinases are comprised of homodimers or heterodimers of creatine kinase B-type protein and creatine kinase M-type protein. Mitochondrial creatine kinases are octomers comprised of either four homodimers of creatine kinase U-type, mitochondrial protein or four creatine kinase S-type, mitochondrial protein homodimers.NCI ThesaurusU.S. National Cancer Institute, 2021
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An enzyme that leaks into the bloodstream in high amounts if a muscle is damaged. Can be used to detect heart attack or muscle damage from other diseases.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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Serum creatine kinase levels (CK) can vary among healthy subjects, even when correcting for muscle mass. Age, gender, race, and physical activity can affect CK.WebMD, 2019
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