Biologically Active Substance
cyclic GMP Audio
cy·clic GMP
Subclass of:
Guanine Nucleotides
Definitions related to cyclic gmp:
  • A cellular regulatory agent that acts as a second messenger. Its levels increase in response to a variety of signals (acetylcholine, insulin, oxytocin) and activates specific protein kinases.
    NCI
    U.S. National Cancer Institute, 2021
  • Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • (cyclic guanosine monophosphate) A chemical in the body that widens blood vessels in the penis. This increases blood flow to the penis, causing an erection.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
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