Pharmacologic Substance
dacomitinib
Brand Names:
Vizimpro
Effect:
Increased Cellular Death
May Treat:
Carcinoma, Non-Small-Cell Lung
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to dacomitinib:
  • A highly selective, orally bioavailable small-molecule inhibitor of the HER family of tyrosine kinases with potential antineoplastic activity. Dacomitinib specifically and irreversibly binds to and inhibits human Her-1, Her-2, and Her-4, resulting in the proliferation inhibition and apoptosis of tumor cells that overexpress these receptors.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called protein tyrosine kinase inhibitors.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.