Pharmacologic Substance
dacomitinib
Brand Names:
Vizimpro
Effect:
Increased Cellular Death
May Treat:
Carcinoma, Non-Small-Cell Lung
More Information:
Definitions related to dacomitinib:
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A highly selective, orally bioavailable small-molecule inhibitor of the HER family of tyrosine kinases with potential antineoplastic activity. Dacomitinib specifically and irreversibly binds to and inhibits human Her-1, Her-2, and Her-4, resulting in the proliferation inhibition and apoptosis of tumor cells that overexpress these receptors.NCI ThesaurusU.S. National Cancer Institute, 2021
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A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called protein tyrosine kinase inhibitors.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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