Pharmacologic Substance
dianhydrogalactitol
Subclass of:
Galactitol
Definitions related to dianhydrogalactitol:
  • A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in disruption of DNA function and cell cycle arrest. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • One of the cytotoxic dihalohexitols that alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in a disruption of DNA function and cell cycle arrest. It has antineoplastic activity and also causes bone marrow toxicity.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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