Pharmacologic Substance
doxazosin mesylate
[ dok-say-zoh-sin meh-zih-layt ]
Effect:
Arterial Vasodilation; Decreased Bladder Sphincter Tone; Decreased Blood Pressure; Venous Vasodilation
May Treat:
Hypertension;
Prostatic Hyperplasia;
Urinary Retention
More Information:
Definitions related to doxazosin mesylate:
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A drug used to treat high blood pressure and urinary problems caused by an enlarged prostate. It relaxes muscle tissue in blood vessels and in the prostate. Cardura is a type of alpha blocker.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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The mesylate salt form of doxazosin, a quinazoline compound with smooth muscle relaxing activity. Doxazosin mesylate selectively antagonizes alpha-1-adrenergic receptors in smooth muscle of the bladder neck and prostate, thereby relaxing the smooth muscle and decreasing the obstruction and urethral resistance seen with benign prostate hyperplasia (BPH). This may improve BPH symptoms. This agent also blocks alpha-1-adrenergic receptors in peripheral vascular smooth muscle, which leads to vasodilatation and a subsequent decrease in peripheral vascular resistance.NCI ThesaurusU.S. National Cancer Institute, 2021
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