Disease or Syndrome
ectodermal dysplasia
[ ek-tuh-durm-al dis-pley-zhuh, -zhee-uh, -zee-uh ]
Subclass of:
Multiple congenital anomalies;
Skin Diseases, Genetic;
Skin Abnormalities
Definitions related to ectodermal dysplasia:
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A group of hereditary disorders involving tissues and structures derived from the embryonic ectoderm. They are characterized by the presence of abnormalities at birth and involvement of both the epidermis and skin appendages. They are generally nonprogressive and diffuse. Various forms exist, including anhidrotic and hidrotic dysplasias, FOCAL DERMAL HYPOPLASIA, and aplasia cutis congenita.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A group of inherited disorders characterized by malformations of the structures that derive from the ectoderm, such as hair, teeth, nails and sweat glands.NCI ThesaurusU.S. National Cancer Institute, 2021
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Ectodermal dysplasia is a group of conditions in which there is abnormal development of the skin, hair, nails, teeth, or sweat glands.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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(ectodermal dysplasia syndrome) The term ''ectodermal dysplasia'' defines a heterogeneous group of heritable disorders of the skin and its appendages characterized by the defective development of two or more ectodermal derivatives, including hair, teeth, nails, sweat glands and their modified structures (i.e. ceruminous, mammary and ciliary glands). The spectrum of clinical manifestations is wide and may include additional manifestations from other ectodermal, mesodermal and endodermal structures.OrphaNetINSERM, 2021
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The ectodermal dysplasias (EDs) comprise a large, heterogeneous group of inherited disorders that are defined by primary defects in the development of 2 or more tissues derived from embryonic ectoderm. The tissues primarily involved are the skin and its appendages (hair follicles, eccrine glands, sebaceous glands, and, nails) and teeth.WebMD, 2019
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Ectodermal dysplasias (ED) are a group of more than 180 disorders that affect the outer layer of tissue of the embryo (ectoderm) that helps make up the skin, sweat glands, hair, teeth, and nails. Symptoms of ED can range from mild to severe and may include teeth abnormalities; brittle, sparse or absent hair; abnormal fingernails;...National Center for Advancing Translational Sciences
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