Disease or Syndrome
encephalomalacia
[ en-sef-uh-loh-muh-ley-shuh, -shee-uh ]
Subclass of:
Brain Diseases
Definitions related to encephalomalacia:
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Encephalomalacia is the softening or loss of brain tissue after cerebral infarction, cerebral ischemia, infection, craniocerebral trauma, or other injury.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Localized atrophy of the brain parenchyma due to aging, hemorrhage, infarct, or inflammation.NCI ThesaurusU.S. National Cancer Institute, 2021
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Softening or loss of brain tissue following CEREBRAL INFARCTION; cerebral ischemia, infection, CRANIOCEREBRAL TRAUMA, or other injury. The term is often used during gross pathologic inspection to describe blurred cortical margins and decreased consistency of brain tissue following infarction. Multicystic encephalomalacia refers to the formation of multiple cystic cavities of various sizes in the cerebral cortex of neonates and infants following injury, most notably perinatal hypoxia-ischemic events. (From Davis et al., Textbook of Neuropathology, 2nd ed, p665; J Neuropathol Exp Neurol, 1995 Mar;54(2):268-75)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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