Disease or Syndrome
encephalomalacia
[ en-sef-uh-loh-muh-ley-shuh, -shee-uh ]
Subclass of:
Brain Diseases
Definitions related to encephalomalacia:
  • Encephalomalacia is the softening or loss of brain tissue after cerebral infarction, cerebral ischemia, infection, craniocerebral trauma, or other injury.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2021
  • Localized atrophy of the brain parenchyma due to aging, hemorrhage, infarct, or inflammation.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Softening or loss of brain tissue following CEREBRAL INFARCTION; cerebral ischemia, infection, CRANIOCEREBRAL TRAUMA, or other injury. The term is often used during gross pathologic inspection to describe blurred cortical margins and decreased consistency of brain tissue following infarction. Multicystic encephalomalacia refers to the formation of multiple cystic cavities of various sizes in the cerebral cortex of neonates and infants following injury, most notably perinatal hypoxia-ischemic events. (From Davis et al., Textbook of Neuropathology, 2nd ed, p665; J Neuropathol Exp Neurol, 1995 Mar;54(2):268-75)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.