Research Activity
equivalence trial
e·quiv·a·lence tri·al
Definitions related to equivalence trial:
  • A clinical trial with the objective of demonstrating clinical insignificance between the responses to two or more treatments.
    NCI
    U.S. National Cancer Institute, 2021
  • A trial with the primary objective of showing that the response to two or more treatments differs by an amount that is clinically unimportant. NOTE: This is usually demonstrated by showing that the true treatment difference is likely to lie between a lower and an upper equivalence margin of clinically acceptable differences.
    CDISC Terminology
    Clinical Data Interchange Standards Consortium (CDISC), 2021
  • Trial that aims to show a new treatment is no better and no worse than the standard treatment.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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