• A condition characterized by the abnormal presence of ERYTHROBLASTS in the circulation of the FETUS or NEWBORNS. It is a disorder due to BLOOD GROUP INCOMPATIBILITY, such as the maternal alloimmunization by fetal antigen RH FACTORS leading to HEMOLYSIS of ERYTHROCYTES, hemolytic anemia (ANEMIA, HEMOLYTIC), general edema (HYDROPS FETALIS), and SEVERE JAUNDICE IN NEWBORN.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2021
• (erythroblastosis fetalis) Hemolytic anemia of the fetus or newborn caused by transplacental transmission of maternally formed antibody, usually secondary to an incompatibility between the blood groups of mother and offspring.
  CRISP Thesaurus
  National Institutes of Health, 2006
• (hemolytic disease of the newborn) A condition of the newborn characterized by the destruction of red blood cells initiated by the transmission of IgG antibodies from mother to child via the placenta.
  NICHD Pediatric Terminology
  U.S. National Cancer Institute, 2021
• (hemolytic disease of the newborn) A disorder of the fetus or newborn that occurs when fetal cells that are coated with IgG alloantibodies from the mother attack antigens inherited from the father. Severity can range from absence of symptoms to death.
  NCI Thesaurus
  U.S. National Cancer Institute, 2021
• Erythroblastosis fetalis is hemolytic anemia in the fetus (or neonate, as erythroblastosis neonatorum) caused by transplacental transmission of maternal antibodies to fetal red blood cells. The disorder usually results from incompatibility between maternal and fetal blood groups, often Rho(D) antigens. Diagnosis begins with prenatal...
  Merck Manuals
  Merck & Co., Inc., 2020
• Erythroblastosis fetalis is hemolytic anemia in the fetus (or neonate, as erythroblastosis neonatorum) caused by transplacental transmission of maternal antibodies to fetal red blood cells. The disorder usually results from incompatibility between maternal and fetal blood groups, often Rho(D) antigens. Diagnosis begins with prenatal...
  Merck Manuals
  Merck & Co., Inc., 2020
• A French midwife was the first to report hemolytic disease of the newborn (HDN) in a set of twins in 1609. In 1932, Diamond and colleagues described the relationship among fetal hydrops, jaundice, anemia, and erythroblasts in the circulation, a condition later called erythroblastosis fetalis.
  Medscape
  WebMD, 2019
• Erythroblastosis fetalis, type of anemia in which the red blood cells (erythrocytes) of a fetus are destroyed in a maternal immune reaction resulting from a blood group incompatibility between the fetus and its mother. This incompatibility arises when the fetus inherits a certain blood factor from...
  Encyclopedia Britannica
  Encyclopedia Britannica, Inc., 2020