Pharmacologic Substance
ethchlorvynol Audio
eth·chlor·vy·nol [ eth-klawr-vahyn-l, -klohr- ]
Effect:
Decreased Organized Electrical Activity
May Treat:
Sleep Initiation and Maintenance Disorders
Definitions related to ethchlorvynol:
  • A member of the class of tertiary carbinols with sedative and hypnotic properties. Ethchlorvynol appears to depress the central nervous system by binding at a benzodiazepine-GABA-A-chloride ionophore receptor complex, located in the limbic, thalamic and hypothalamic regions of the central nervous system (CNS). This increases the frequency of chloride channel opening, allowing the flow of chloride ions into the neuron and ultimately leading to membrane hyperpolarization and a decrease in neuronal excitability.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A sedative and hypnotic that has been used in the short-term management of INSOMNIA. Its use has been superseded by other drugs.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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