Pharmacologic Substance
exemestane
[ ek-seh-meh-stayn ]
Brand Names:
Aromasin
Effect:
Decreased Ovarian Estrogen Secretion
May Treat:
Breast Neoplasms
More Information:
Definitions related to exemestane:
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A drug used to treat advanced breast cancer and to prevent recurrent breast cancer in postmenopausal women who have already been treated with tamoxifen. It is also being studied in the treatment of other types of cancer. Aromasin causes a decrease in the amount of estrogen made by the body. It is a type of aromatase inhibitor.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A synthetic androgen analogue. Exemestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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