Pharmacologic Substance
ezetimibe
Brand Names:
Nexlizet; Roszet; Vytorin; Zetia
Effect:
Decreased Cholesterol Absorption
May Treat:
Hypercholesterolemia; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to ezetimibe:
  • An azetidine derivative and ANTICHOLESTEREMIC AGENT that inhibits intestinal STEROL absorption. It is used to reduce total CHOLESTEROL; LDL CHOLESTEROL, and APOLIPOPROTEINS B in the treatment of HYPERLIPIDEMIAS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • An azetidinone derivative and a cholesterol absorption inhibitor with lipid-lowering activity. Ezetimibe appears to interact physically with cholesterol transporters at the brush border of the small intestine and inhibits the intestinal absorption of cholesterol and related phytosterols. As a result, ezetimibe causes a decrease in the level of blood cholesterol or an increase in the clearance of cholesterol from the bloodstream. Overall, the following effects observed are a reduction of hepatic cholesterol stores and a reduction of total cholesterol, LDL cholesterol, and other triglycerides in the blood.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
Try this search on: Farlex, Merriam-Webster, Oxford Dictionary, or Wordnik

This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.